Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes
June 25, 2021
DOI: 10.1056/NEJMoa2107519
Abstract
BACKGROUND
Tirzepatide is a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist that is under development for the treatment of type 2 diabetes. The efficacy and safety of once-weekly tirzepatide as compared with semaglutide, a selective GLP-1 receptor agonist, are unknown.